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I ricercatori utilizzano i topi in molti studi perché, nonostante la differenza dei periodi di attività, hanno molto in comune con gli esseri umani per quanto riguarda la genetica e il funzionamento meccanico interno del corpo. I geni, gli orologi molecolari e altri elementi strutturali che entrano in gioco durante il processo di utilizzo dei muscoli, la produzione di energia e il metabolismo sono simili a quelli degli esseri umani.
Ciò che è immediatamente evidente e applicabile alla salute umana è l’importanza di mantenere un ritmo circadiano sano. Anche se c’è ancora molto da imparare sui meccanismi coinvolti, è chiaro che i ritmi circadiani hanno un impatto sulla salute e sulle funzioni di tutto l’organismo: i tessuti periferici hanno i loro orologi circadiani e i ritmi circadiani influenzano persino le attività molecolari.
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Al mattino, dopo il sonno notturno, il corpo si risveglia terminando la produzione di melatonina (ormone del sonno) e aumentano i livelli di cortisolo e testosterone, for every poter affrontare la nuova giornata con energia.
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Gli orologi circadiani nel muscolo regolano l'efficienza energetica e la risposta all'esercizio fisico
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